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Dupuytren’s Contracture / Xiaflex Injection

Dupuytren’s disease is an abnormal thickening of the tissue just beneath the skin known as fascia. This thickening occurs in the palm and can extend into the fingers. Firm pits, nodules and cords may develop that can cause the fingers to bend into the palm, in which case it is described as Dupuytren’s contracture.

Treatment

In mild cases, especially if hand function is not affected, only observation is needed. For more severe cases, various treatment options are available in order to straighten the finger(s). These options may include collagenase injection (XIAFLEX injection), needle aponeurotomy or open surgery. Xiaflex injection is a technique where a small amount of medicine is injected into the Dupuytren’s tissue, weakening it so that the finger can be manipulated manually to make it straighter. Needle aponeurotomy is a method where a needle is placed through the skin and used to cut the Dupuytren’s tissue. Both collagenase injection and needle aponeurotomy are office procedures.